Yes, it does have using age limited. Since the matrix electrode is made of biocompatible stainless steel materials, which has been removed non-biocompatible ions such as manganese, chromium and nickel. There would be appear the surface oxidation or other electrochemical phenomena around the electrode needles after a certain number of electroporation. There phenomena may reduce the transfection efficiency of electroporation. So that, when the matrix electrode is reused about 100 times, changing a new matrix electrode is suggested.